WIN SYMPOSIUM

Co-Chairs

Wafik S. El-Deiry, MD, PhD, FACP, Chair, WIN Consortium, Director, Legorreta Cancer Center Brown University, Director, Joint Program in Cancer Biology, Brown University and Brown University Health; Associate Dean, Oncologic Sciences, Warren Alpert Medical School, Brown University; Attending Physician, Hematology/Oncology, Brown University Health Mencoff Family University; Professor of Medical Science, Professor of Pathology and Laboratory Medicine, Brown University; Professor, American Cancer Society Research Professor

Razelle Kurzrock, MD, FACP, Chief Medical Officer, WIN Consortium; Professor of Medicine, Associate Director, Clinical Research, Linda T. and John A. Mellowes Chair of Precision Oncology, MCW Cancer Center and Linda T. & John A. Mellowes Center for Genomic Sciences and Precision Medicine

MULTI-OMICS

Chair

Arutha Kulasinghe, PhD, Associate Professor, Frazer Institute, University of Queensland; Founding Scientific Director, Queensland Spatial Biology Centre

WIN SYMPOSIUM

MULTI-OMICS

SESSION 1

From Base Pairs To Better Care:

AI and Omics in Precision Oncology

Multi-Omic Profiling and Clinical Decision Support in Precision Oncology

David Spetzler, PhD, MBA, MS,  President, Caris Life Sciences

Integrating Omics and AI for Next-Gen Precision Oncology

Keith T. Flaherty, MD, FAACR, Director of Clinical Research, Massachusetts General Cancer Center; Professor of Medicine, Harvard Medical School;
President-Elect: 2025-2026, American Association for Cancer Research (AACR) 

Real-World Data and AI in Precision Oncology: Making Data Work for Patients – Q&A

MODERATOR: Jeff Elton, PhD, Vice Chairman, Founding CEO
ConcertAI

PANELISTS: David Spetzler, PhD, MBA, MS, President, Caris Life Sciences

Keith T. Flaherty, MD, FAACR, Director of Clinical Research, Massachusetts General Cancer Center; Professor of Medicine, Harvard Medical School;
President-Elect: 2025-2026, American Association for Cancer Research (AACR) 

Multi-Omics Approaches in Precision Medicine

CHAIR –  Arutha Kulasinghe, PhD, Associate Professor, Frazer Institute, University of Queensland; Founding Scientific Director, Queensland Spatial Biology Centre

Kurt A. Schalper, MD, PhD, Associate Professor of Pathology and Medicine (Medical Oncology), Yale School of Medicine; Director Translational Immuno-Oncology Laboratory, Yale Cancer Center

Justin Davis, PhD, Vice President of Research and Developoment, Ignite Proteomics

Hoifung Poon, PhD, General Manager, Microsoft Research; Affiliated Faculty, University of Washington Medical School

Michael Smith, PhD, Associate Director, Specialist, Single Cell and Spatial Technologies
Illumina

Panel Discussion

WIN SYMPOSIUM

MULTI-OMICS

SESSION 2

The Evolution of Precision Oncology:

Integrating MRD, AI, and Beyond

Precision Cancer Consortium

Gabriele Allegri, MBA, Vice President, Global Commercial Precision Medicine, Johnson & Johnson Innovative Medicine

Shruti Mathur, MS, Pharma Diagnostic Strategy Leader, Global Product Strategy (GPS), Genentech

Daryl Pritchard, PhD, Interim President, Personalized Medicine Coalition

Keith T. Flaherty, MD, FAACR, Director of Clinical Research, Massachusetts General Cancer Center; Professor of Medicine, Harvard Medical School;
President-Elect: 2025-2026, American Association for Cancer Research (AACR) 

SESSION 3

The Shifting Landscape:

Tumor Plasticity and Resistance

Mathematical and Evolutionary Modeling in Precision Radiation Oncology

Jacob Scott, MD, DPhil, Professor and Staff Physician-Scientist, CWRU School of Medicine and Cleveland Clinic

Plasticity and Persistence: The Role of EMT in Cancer Progression and Therapy Resistance

Sendurai A. Mani, PhD, Professor of Pathology and Laboratory Medicine, Brown University; Associate Director of Translational Oncology, Brown University Legorreta Cancer Center

Targeting Molecularly Defined Subsets: Challenges in Translational Oncology

Benedito A. Carneiro, MD, MS, Director, Clinical Research
Director, Cancer Drug Development; Associate Director, Division of Hematology/Oncology
Legorreta Cancer Center, Brown University Health

Spatial-Omics Applications

CHAIR: Arutha Kulasinghe, PhD, Associate Professor, Frazer Institute, University of Queensland; Founding Scientific Director, Queensland Spatial Biology Centre

Sizun Jiang, PhD, Principal Investigator, Center for Virology & Vaccine Research, Beth Israel Deaconess Medical Center, Harvard Medical School

Jiwoon Park, PhD, Postdoctoral Associate, Harvard Medical School and Weill Cornell Medicine; Member, Laboratories of Drs. George Church and Christopher Mason

Michael Schnall-Levin, PhD, Chief Technology Officer, Founding Scientist, 10X Genomics

Abhishek Aggarwal, PhD, Group Leader Pathology, Gilead Sciences

Panel Discussion

Non – CME Session Industry Perspectives

illumina, 10X Genomics, Stellaromics

WIN SYMPOSIUM

MULTI-OMICS

SESSION 4

From Targets to Trials:
Translating Discovery into Impact

Beyond Checkpoint Inhibitors: Targeted Immunotherapeutic Approaches for the Management of Solid Tumors

Matthew Hadfield, DO, Assistant Professor of Medicine, Phase 1 Clinical Trials, Cutaneous Malignancies, The Warren Alpert Medical School of Brown University 

Implementing Molecular Profiling in Early Phase Clinical Trials: Precision from Bench to Bedside

Apostolia M. Tsimberidou, MD, PhD, FASCO, FAAAS, Tenured Professor, Department of Investigational Cancer Therapeutics, Division of Cancer Medicine, The University of Texas MD Anderson Cancer

Q&A

Matthew Hadfield, DO, Assistant Professor of Medicine, Phase 1 Clinical Trials, Cutaneous Malignancies, The Warren Alpert Medical School of Brown University 

Apostolia M. Tsimberidou, MD, PhD, FASCO, FAAAS, Tenured Professor, Department of Investigational Cancer Therapeutics, Division of Cancer Medicine, The University of Texas MD Anderson Cancer

Non- CME Session: Venture Philanthropy

Eric Heil, MBA, Managing Partner, Medical Excellence Capital

John Lehr, President & CEO, Parkinson’s Foundation

Dr. Blaine Robinson, PhD, Vice President of the Therapy Acceleration Program (TAP), Blood Cancer United

eNSCLC Testing

Kurt A. Schalper, MD, PhD, Associate Professor of Pathology and Medicine (Medical Oncology), Yale School of Medicine; Director Translational Immuno-Oncology Laboratory, Yale Cancer Center

Non – CME Session: AI & Digital Pathology

Shruti Mathur, MS, Pharma Diagnostic Strategy Leader, Global Product Strategy (GPS), Genentech

Kimbery Gasaud,MBA, Principal Consultant, JK Life Sciences LLC

Paul Beresford, PhD, PathAI

Keith Wharton, Roche Diagnostics

Omics Into the Clinic – The Next Step

CHAIR: Sizun Jiang, PhD, Principal Investigator, Center for Virology & Vaccine Research, Beth Israel Deaconess Medical Center, Harvard Medical School

Arutha Kulasinghe, PhD, Associate Professor, Frazer Institute, University of Queensland; Founding Scientific Director, Queensland Spatial Biology Centre

Thazin Nwe Aung, MD
Associate Research Scientist in Pathology, Yale University

Clemens Duerrschmidt, PhD, Quanterix

Panel Discussion

CHAIR: Sizun Jiang, PhD, Principal Investigator, Center for Virology & Vaccine Research, Beth Israel Deaconess Medical Center, Harvard Medical School

Laura Dillon, PhD, Senior Director, Partnership Strategy Lead, External R&D and Innovation, AstraZeneca

Jared K. Burks, PhD, Director, Flow Cytometry & Cellular Imaging Core Facility MD, Anderson Cancer Center

Hoifung Poon, PhD, General Manager, Microsoft Research

WIN SYMPOSIUM

MULTI-OMICS

Transforming Pediatric Oncology: The Power of Precision Medicine

Giselle L. Sholler, MD, Division Chief, Pediatric Hematology/Oncology/BMT, Penn State Hershey Children’s Hospital; Professor, Pediatrics and Pharmacology; Founder & Chair, Beat Childhood Cancer Consortium

Wei Zhang, PhD, Hanes and Willis Family Professor in Cancer; Director, Cancer Genomics and Precision Oncology, Wake Forest Baptist Comprehensive Cancer Center

Elias Sayour, MD, PhD, Professor, Neurosurgery and Pediatrics;  Assistant Dean,  Clinical Research, UF College of Medicine, Program Co-leader,  UF Health Cancer Center Immuno-Oncology and Microbiome (IOM) Program

Pei Wang, PhD, Professor, Genetic and Genomic Sciences, Icahn School of Medicine at Mount Sinai

Abigail Moore

Informing therapy decisions for improved patient care

Ashley Varghese, PharmD, RPh

Liquid Biopsies and Resistance Monitoring in Targeted Therapies 

Pashtoon Kasi, MD, MS, Medical Director, GI Medical Oncology, City of Hope

Liquid Biopsies in Clinical Practice: Transforming Precision Oncology Through Molecular Monitoring

Hatim Husain, MD, Associate Professor, University of California, San Diego 

Multi-Omics

CHAIR: Jiwoon Park, PhD, Postdoctoral Associate, Harvard Medical School and Weill Cornell Medicine; Member, Laboratories of Drs. George Church and Christopher Mason

Jared K. Burks, PhD, Director, Flow Cytometry & Cell Imaging Core Facility, Department of Hematopoietic Biology & Malignancies,Division of Cancer Medicine; Associate Director of Shared Resources CCSG, Department of CCSG; Professor, Department of Hematopoietic Biology & Malignancies, Division of Cancer Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX

Aruna Ayer, PhD, VP, Multiomics, Innovation and Scientific Affairs, BD Biosciences

Harsha Gowda, PhD, Senior Principal Scientist, Director, Research & Lab Operations, Signios Bio

Panel Discussion

Non- CME Industry Perspectives

Vizgen, Stellaromics, Signios Bio

WIN SYMPOSIUM

Co-Chairs

Wafik S. El-Deiry, MD, PhD, FACP, Chair, WIN Consortium, Director, Legorreta Cancer Center Brown University, Director, Joint Program in Cancer Biology, Brown University and Brown University Health; Associate Dean, Oncologic Sciences, Warren Alpert Medical School, Brown University; Attending Physician, Hematology/Oncology, Brown University Health Mencoff Family University; Professor of Medical Science, Professor of Pathology and Laboratory Medicine, Brown University; Professor, American Cancer Society Research Professor

Razelle Kurzrock, MD, FACP, Chief Medical Officer, WIN Consortium; Professor of Medicine, Associate Director, Clinical Research, Linda T. and John A. Mellowes Endowed Chair of Precision Oncology, MCW Cancer Center and Linda T. & John A. Mellowes Center for Genomic Sciences and Precision Medicine

PM OUTSIDE OF ONCOLOGY

Chair

Howard McLeod, PharmD, Professor & Center Director
Utah Tech University

WIN SYMPOSIUM

PM OUTSIDE OF ONCOLOGY

SESSION 1

Precision For All:

Global Access, Real Cases, and Implementation Science

Results and Future Direction from WIN’s Data Science Paper

Gerald Batist, MD, Director, Segal Cancer Centre, Jewish General Hospital; Director, McGill Centre for Translational Research in Cancer; Professor, Department of Oncology, McGill University

When Precision Gets Personal: WIN Consortium International Molecular Tumor Board Live

Wafik S. El-Deiry, MD, PhD, FACP, Chair, WIN Consortium, Director, Legorreta Cancer Center Brown University, Director, Joint Program in Cancer Biology, Brown University and Brown University Health; Associate Dean, Oncologic Sciences, Warren Alpert Medical School, Brown University; Attending Physician, Hematology/Oncology, Brown University Health Mencoff Family University; Professor of Medical Science, Professor of Pathology and Laboratory Medicine, Brown University; Professor, American Cancer Society Research Professor

Razelle Kurzrock, MD, FACP, Chief Medical Officer, WIN Consortium; Professor of Medicine, Associate Director, Clinical Research, Linda T. and John A. Mellowes Endowed Chair of Precision Oncology, MCW Cancer Center and Linda T. & John A. Mellowes Center for Genomic Sciences and Precision Medicine

SESSION 2

Expanding the Precision Frontier

Precision Oncology in the Immunotherapy Era: Biomarkers and Clinical Trial Innovation

Lillian Siu, MD, President, AACR 2025-2026; Director, Phase I Clinical Trials Program; Co-Director, Robert and Maggie Bras and Family Drug Development Program Clinical Lead, Tumor Immunotherapy Program; BMO Chair, Precision Cancer Genomics, Princess Margaret Cancer Centre Professor of Medicine, University of Toronto

The Microbiome and Its Role in Cancer Development and Treatment Response

Sabine Hazan, MD, CEO, Ventura Clinical Trials; CEO, Progenabiome

Precision Therapy for Rare Disease

Marni Falk, MD, Executive Director, Mitochondrial Medicine Frontier Program
CHOP 

Sundeep Dugar, PhD, Chief Executive Officer, Aayam Therapeutics 

Chris Jeffers, Senior Vice President, Life Sciences, BioAdvisory Services

Howard McLeod, PharmD, Professor & Center Director
Utah Tech University

Mimi Lee, MD, PhD, Program Manager, Advanced Projects Research Agency for Health (ARPA-H)

Niven R. Narain, PhD, President and CEO, BPGbio Inc

Chris Marsh, Managing Director, Private Wealth Advisor,UBS 

WIN SYMPOSIUM

PM OUTSIDE OF ONCOLOGY

SESSION 3

Advances in Precision Oncology:
From Genomics to Targeted Therapies

Breaking the Glass Ceiling: Targeting KRAS in Pancreatic Cancer

Michael Pishvaian, MD, Associate Professor, Department of Oncology, Johns Hopkins University

Kim Reiss, MD, Associate Professor of Medicine (Hematology-Oncology), Hospital of the University of Pennsylvania

Charting the Future of Cancer Care: Precision Oncology and the Power of Genomics

Vivek Subbiah, MD,
Chief, Early-Phase Drug Development, Sarah Cannon Research Institute

Molecular Pathology as a Driver of Precision in Urological Cancers

Liang Cheng, MD, Professor and Vice Chair, Translational Research; Director of Anatomic and Molecular Pathology, Department of Pathology and Laboratory Medicine, Brown University Medical School, Lifespan Academic Medical Center

Epigenetic Plasticity and Tumor Evolution: Mechanisms of Resistance in Precision Oncology

Johnathan R. Whetstine, PhD, Director, Cancer Epigenetics Institute, Director, Geonomics Resource, Fox Chase Cancer Center

Panel Q&A

Vivek Subbiah, MD, Chief, Early-Phase Drug Development, Sarah Cannon Research Institute

Liang Cheng, MD, Professor and Vice Chair, Translational Research; Director of Anatomic and Molecular Pathology, Department of Pathology and Laboratory Medicine, Brown University Medical School, Lifespan Academic Medical Center

Johnathan R. Whetstine, PhD, Director, Cancer Epigenetics Institute, Director, Geonomics Resource, Fox Chase Cancer Center

Companion Diagnostics in Hereditary and Chronic Diseases – Development, Regulatory Approval, and Commercialization – Non-CME Discussion

Huw Ricketts PhD, Senior Director, CLIA Business Development, QIAGEN

Tricia Carrigan, PhD, BC Biosolutions

Arushi Agarwal, MS,  Partner, Health Advances

Melissa Reuter, MS, MBA, Director, Precision Medicine Program Strategy, GSK

Non – CME – dSTRIDE™-HR: A Functional Biomarker for In Situ, ‘real-time’ Detection and Quantification of Homologous Recombination Activity.

Magda Kordon-Kiszala, PhD, CEO and co-founder, intoDNA

WIN SYMPOSIUM

PM OUTSIDE OF ONCOLOGY

SESSION 4

Precision Without Borders:
From Trial Evolution to Global Impact

Building Precision Oncology Infrastructure in Low- and Middle-Income Countries

Sewanti Limaye, MD, Director, Medical & Precision Oncology; Director Clinical and Translational Oncology Research, Sir HN Reliance Foundation Hospital & Research Centre, Mumbai, India; Founder, Nova Precision AI; Co-Founder, Iylon Precision Oncology; Co-Chair, Asia Pacific Coalition Against Lung Cancer; Co-Chair,  Asia Pacific Immuno-Oncology; Member,  WIN Consortium

Co-targeting KIT/PDGRFA and Genomic Integrity in Gastrointestinal Stromal Tumors

Lori Rink, PhD, Associate Professor, Fox Chase Cancer Center

Abstract Presentations

WIN Consortium Update 2025, Progress update, trial design innovation, and technology integration across consortium studies.

Wafik S. El-Deiry, MD, PhD, FACP, Chair, WIN Consortium, Director, Legorreta Cancer Center Brown University, Director, Joint Program in Cancer Biology, Brown University and Brown University Health; Associate Dean, Oncologic Sciences, Warren Alpert Medical School, Brown University; Attending Physician, Hematology/Oncology, Brown University Health Mencoff Family University; Professor of Medical Science, Professor of Pathology and Laboratory Medicine, Brown University; Professor, American Cancer Society Research Professor

Razelle Kurzrock, MD, FACP, Chief Medical Officer, WIN Consortium; Professor of Medicine, Associate Director, Clinical Research, Linda T. and John A. Mellowes Endowed Chair of Precision Oncology, MCW Cancer Center and Linda T. & John A. Mellowes Center for Genomic Sciences and Precision Medicine

AI in Precision Medicine

Dr. Ganhui Lan VP, Data Science & Machine Learning, Genentech

Dr. Xiaoyan Wang Research Professor, Department of Health Policy and Management, Tulane University Chief Scientist, SVP, Intelligent Medical Objects

Dr. Ahmad P. Tafti Assistant Professor, School of Computing and Information,School of Health and Rehabilitation Sciences, University of Pittsburgh Interim Director, Division of Scientific Affairs, Computational Pathology AI Center of Excellence

Jen Gilburg (moderator) Deputy Secretary of Technology and Entrepreneurship, Dept. of Community and Economic Development, Commonwealth of Pennsylvania